ZEJULA (niraparib) Dosing and Adverse Reaction Management
EXPLORE DOSING FOR ZEJULA IN PATIENTS WITH OVARIAN CANCER
IN THE FOLLOWING TREATMENT SETTINGS:
ZEJULA: Convenient
once-daily oral dosing1
Once-Daily
Oral Monotherapy

Taken With
or Without Food

Taken Any Time
of the Day

Bedtime administration may be a potential method for managing nausea
ZEJULA should be taken at approximately the same time each day1
Drug-Drug
Interactions

No specific drug-drug interactions have been reported with ZEJULA†
†No clinical drug interaction studies have been performed with ZEJULA.
Once-daily oral dosing and appropriate dose modification
support long-term treatment with ZEJULA1
Recommended ZEJULA starting dose by indication1


For patients with moderate hepatic impairment, reduce the starting dosage of ZEJULA to 200 mg once daily. Monitor patients for hematologic toxicity and reduce the dose further, if needed.1